Table 1. The candidate COGs interacting with circadian enhancers via invariant cohesin-mediated loops.

Gene Symbol	Circadian Phase (CT)	Transcription Factor	Transcription Factor binding site position (kb)	Cohesin KO-CN Log2-Fold-Change (LFC)
Tmtc2	11	Bmal1	200	-2.5
Rnf43	7.5	Bmal1	39	-1.5
Phldb2	7	Bmal1	126	-1.1
Cdo1	6	Bmal1	-130, -121	-1.2
Kcnb1	11	Bmal1	-128	-1
Atr	11	Bmal1	-317,-315,-305	-1.4
1200009I06Rik	23.5	Nr1d1	-30	-0.8
Ahnak	20.5	Nr1d1	106, 108, 131	-0.9
Dapk1	23.5	Nr1d1	-121, -116, 129, 135	-1.2
Npas2	1	Nr1d1	-179, -169	-1.1