Skip to main content
. 2016 May 2;11(5):e0154815. doi: 10.1371/journal.pone.0154815

Fig 5. Compared to peripheral blood, tumor-infiltrating IL-10-expressing B cells were further upregulated and CD4+ cytotoxic T cells were downregulated.

Fig 5

(A) The frequencies of IL-10-expressing B cells in the peripheral blood and resected tumor of the same subject. (B) The frequencies of granzyme A, granzyme B and perforin-expressing in the peripheral blood ans resected tumors of the same subject. Paired t test. *** P < 0.001. ** P < 0.01. (C) The correlations between the frequencies of tumor-infiltrating IL-10-expressing B cells and tumor-infiltrating granzyme A, granzyme B and perforin-expressing CD4+ T cells in HCC patients. Pearson correlation test. P < 0.05 is considered significant.