Table 2. Effect of pulchrin A and control drugs on cancer and normal cells at 24 h by MTT assay.
The experiment was done in triplicate. Data are reported as mean ± SD.
Compounds | Cell lines | IC50 (μM) | ||
---|---|---|---|---|
24 h | 48 h | 72 h | ||
Pulchrin A | CAOV-3 | 22.31 ± 0.42 | 19.25 ± 0.64 | 5.35 ± 0.21 |
SKOV-3 | 31.63 ± 0.35 | 20.21 ± 0.21 | 13.03 ± 0.18 | |
T1074 | >100 | >100 | >100 | |
Cisplatin | CAOV-3 | 30.56 ± 0.33 | 10.17 ± 0.16 | 6.04 ± 0.09 |
SKOV-3 | 42.50 ± 0.28 | 13.06 ± 0.11 | 9.20 ± 0.81 | |
T1074 | >100 | >100 | >100 |