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. 2016 May;137(5):1413–1422.e12. doi: 10.1016/j.jaci.2016.02.001

Table E3.

Correlations between clinical outcomes and QCT parameters for asthmatic patients (upper values) and patients with COPD (lower values)

RV/TLC KCO (% predicted) Sputum eosinophils (%)* Sputum neutrophils (%)* Blood eosinophils* Blood neutrophils* AQLQ* ACQ6* SGRQ total*
Mean LA/BSA (mm2/m2) −0.147
−0.171
−0.163
−0.089
0.031
0.121
−0.134
0.036
−0.019
−0.033
−0.183†
−0.11
0.113
NA
−0.152†
NA
NA
−0.034
Mean TA/BSA (mm2/m2) −0.115
−0.198
−0.153
−0.084
0.044
0.096
−0.120
0.042
−0.011
−0.033
−0.188†
−0.101
0.135
NA
−0.164*
NA
NA
−0.040
Mean WA/BSA (mm2/m2) −0.078
−0.217
−0.153
−0.075
0.064
0.086
−0.119
0.064
−0.003
−0.027
−0.196†
−0.28
0.171†
NA
−0.179*
NA
NA
−0.059
Mean %WA 0.237‡
0.130
0.201†
0.053
−0.003
−0.236
0.094
−0.026
0.037
−0.07
0.128
0.216
−0.049
NA
0.120
NA
NA
0.010
MLDE/I 0.481‡
0.510‡
−0.146
−0.466‡
0.026
−0.170
0.119
0.185
0.081
0.033
0.053
0.135
−0.015
NA
0.030
NA
NA
0.230†
Perc15 (HU) −0.196†
−0.271†
−0.013
0.477‡
−0.239†
0.047
0.084
0.005
−0.007
0.142
0.022
−0.018
−0.028
NA
0.001
NA
NA
0.108
LAC-D−950 −0.162
−0.170
0.083
0.484‡
0.272‡
0.181
−0.083
0.193
0.156
0.025
−0.074
−0.021
0.006
NA
0.024
NA
NA
−0.061

ACQ6, Asthma Control Questionnaire (first 6); AQLQ, Asthma Quality of Life Questionnaire; NA, not applicable; RV/TLC, residual volume/total lung capacity; SGRQ, St Georges Respiratory Questionnaire.

Pearson correlation coefficient for parametric data are shown. *Otherwise, the Spearman correlation coefficient for nonparametric data is shown.

P < .05 and ‡P < .005.