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Interleukin-1 beta (IL-1β) induction by Escherichia coli RNA, (A) E. coli RNA stimulated IL-1β secretion by hepatic stellate cells (HSC)-T6 cells, which was abrogated upon RNase A digestion, (B) IL-1β expression was elevated, whereas pro-IL-1β expression was reduced in HSC-T6 cells after E. coli RNA transfection. *p < 0.01. Data are expressed as mean ± standard deviation. E. c: Escherichia coli RNA; RNa: RNase A.
