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. 2016 Apr 22;11:1643–1661. doi: 10.2147/IJN.S101030

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© 2016 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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The antitumor efficacy against subcutaneous tumor-bearing nude mice; 10 mg/kg DTX or equivalent T2K or TGK micelles was administrated at day 1, day 4, and day 7.

Notes: (A) The relative tumor volume–time curve. (B) The body weight change after administration of DTX, TGK micelles, or T2K micelles. (C) Photographs of tumors from each group. (D) The weights of excised tumors from subcutaneous tumor-bearing nude mice at the time of execution. Values are expressed as mean ± SD (n=5). *P<0.05.

Abbreviations: DTX, docetaxel; T2K micelles, micelles composed of TPGS/T2K (n:n =40:60); TGK micelles, micelles composed of TPGS/TGK (n:n =40:60); SD, standard deviation; TPGS, d-α-tocopheryl polyethylene glycol 1000 succinate.