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. 2016 Apr 22;11:1643–1661. doi: 10.2147/IJN.S101030

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© 2016 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Characteristics of TGK micelles and T2K micelles.

Notes: Size distribution of DTX-loaded TGK micelles (A) and T2K micelles (B). (C) Plot of UV absorption of I₂ versus concentration of TPGS/T2K (n:n =40:60) and TPGS/TGK (n:n =40:60). CMC value was calculated by corresponding polymer concentration at which a sharp increase in absorbance was observed. (D) Amount of DTX retained in T2K micelles and TGK micelles at corresponding time, in 48 hours. Stability was indicated by the percentage of DTX remaining in the micelles. Values are expressed as mean ± SD (n=3).

Abbreviations: DTX, docetaxel; T2K micelles, micelles composed of TPGS/T2K (n:n =40:60); TGK micelles, micelles composed of TPGS/TGK (n:n =40:60); UV, ultraviolet; TPGS, d-α-tocopheryl polyethylene glycol 1000 succinate; TGK, mPEG2K-GK8-α-TOS conjugate; T2K, mPEG2K-α-TOS conjugate; α-TOS, α-tocopherol succinate; CMC, critical micelle concentration; SD, standard deviation; h, hour.