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. 2016 Apr 22;11:1643–1661. doi: 10.2147/IJN.S101030

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© 2016 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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FRET analysis of DiO/DiI-loaded T2K micelles and TGK micelles.

Notes: Emission spectra of DiO/DiI-loaded T2K micelles, TGK micelles, DiO/DiI-loaded T2K micelles and TGK micelles (A), and the ratio of IR/(IR+IG) incubated at 37°C for 2 hours with or without MMP-2/9 (B). Values are expressed as mean ± SD (n=3). **P<0.01.

Abbreviations: T2K micelles, micelles composed of TPGS/T2K (n:n =40:60); TGK micelles, micelles composed of TPGS/TGK (n:n =40:60); DiO, 3,3′-dioctadecyloxacarbocyanine perchlorate; DiI, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; IG, fluorescence intensity at 510 nm; IR, fluorescence intensity at 565 nm; MMP, matrix metalloproteinase; TPGS, d-α-tocopheryl polyethylene glycol 1000 succinate; SD, standard deviation.