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. 2016 Apr 22;11:1643–1661. doi: 10.2147/IJN.S101030

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© 2016 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Cytotoxicity of micelles to cell lines expressing different level of MMPs.

Notes: Cytotoxicity of blank T2K and TGK micelles in MCF-7 (A) and HT1080 (B) cells at 48 hours. Cytotoxicity of DTX-loaded T2K micelles and TGK micelles in MCF-7 cells (C) and HT1080 cells (D) at 48 hours. Tween 80 was used as control. Values are expressed as mean ± SD (n=3). HT1080 is the human fibrosarcoma cell line, MCF-7 is the human breast adenocarcinoma cell line.

Abbreviations: DTX, docetaxel; T2K micelles, micelles composed of TPGS/T2K (n:n =40:60); TGK micelles, micelles composed of TPGS/TGK (n:n =40:60); SD, standard deviation; TPGS, d-α-tocopheryl polyethylene glycol 1000 succinate; MMPs, matrix metalloproteinases.