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. 2016 Apr 26;11:1687–1700. doi: 10.2147/IJN.S103332

Figure 6.

Figure 6

Concentration- and time-dependent cytotoxicity assays in LNPaC spheroids.

Notes: Microplate-based CellTiter Fluor® assay of formed spheroid culture of human prostate carcinoma cells, LNPaC, measured (A) at Brb-equivalent concentration range of 0.15–20 μM, or (B) at “cross-section” concentration of 5 μM, after incubation for 48 hours, at 37°C, 5% CO2 conditions (n=4–5, mean ± SE).

Abbreviations: Brb, berberine; mMic, mixed micelle; SE, standard error.