Table 1.
Baseline Demographic Characteristics
| Group; No. (%) of Patients or Mean ± SD | ||||
|---|---|---|---|---|
|
| ||||
| Parameter | No Heparin (n = 268) | Prophylactic Heparin (n = 266) | Therapeutic Heparin (n = 13) | Overall (n = 547) |
| Sex, male | 158 (59.0) | 162 (60.9) | 8 (62) | 328 (60.0) |
|
| ||||
| Prior transplant loss | 33 (12.3) | 11 (4.1) | 4 (31) | 48 (8.8) |
|
| ||||
| Transplant type | ||||
| Living | 148 (55.2) | 134 (50.4) | 5 (38) | 287 (52.5) |
| Deceased donor | 120 (44.8) | 132 (49.6) | 8 (62) | 260 (47.5) |
|
| ||||
| Age (years) | 50.4 ± 13.1 | 52.4 ± 13.2 | 57.5 ± 16.3 | 51.5 ± 13.3 |
|
| ||||
| BMI (kg/m2) | 25.7 ± 5.3 | 26.4 ± 4.7 | 26.9 ± 5.5 | 26.1 ± 5.0 |
|
| ||||
| Laboratory investigations | ||||
| SCr (μmol/L) | 546.8 ± 239.5 | 545.9 ± 261.4 | 485.0 ± 192.9 | 544.9 ± 249.2 |
| Platelets (× 109/L) | 177.1 ± 63.2 | 184.5 ± 57.5 | 168.9 ± 48.1 | 180.5 ± 60.2 |
| Hemoglobin (g/L) | 105.8 ± 15.4 | 104.4 ± 14.5 | 104.7 ± 12.5 | 105.1 ± 14.9 |
| PTT (s) | 32.5 ± 8.0 | 31.65 ± 8.49 | 40.4 ± 16.6 | 32.3 ± 8.6 |
| INR | 1.1 ± 0.2 | 1.09 ± 0.15 | 1.2 ± 0.1 | 1.1 ± 0.2 |
|
| ||||
| Length of admission (days) | 7.8 ± 12.9 | 8.5 ± 17.4 | 18.9 ± 17.4 | 8.3 ± 15.4 |
|
| ||||
| Transplant year | ||||
| 2008–2010 | 243 (90.7) | 14 (5.3) | 8 (62) | 265 (48.4) |
| 2011–2013* | 25 (9.3) | 252 (94.7) | 5 (38) | 282 (51.6) |
|
| ||||
| Comorbid conditions within 6 months of transplant date | ||||
| Diabetes mellitus | 82 (30.6) | 100 (37.6) | 3 (23) | 185 (33.8) |
| Hypertension | 210 (78.4) | 229 (86.1) | 9 (69) | 448 (81.9) |
| Malignancy | 22 (8.2) | 22 (8.3) | 2 (15) | 46 (8.4) |
| Coronary artery disease | 52 (19.4) | 65 (24.4) | 5 (38) | 122 (22.3) |
| Cerebrovascular events | 9 (3.4) | 9 (3.4) | 0 (0) | 18 (3.3) |
| Myocardial infarction | 11 (4.1) | 18 (6.8) | 2 (15) | 31 (5.7) |
| Congestive heart failure | 17 (6.3) | 14 (5.3) | 1 (8) | 32 (5.9) |
| Dysrhythmia | 11 (4.1) | 13 (4.9) | 1 (8) | 25 (4.6) |
BMI = body mass index, INR = international normalized ratio, PTT = partial thromboplastin time, SCr = serum creatinine, SD = standard deviation.
*
Up to and including July 31, 2013.