Table 2.

Comparison of Hematological and Coagulation Parameters in Patients with Major Bleeding Events

	Group; Mean ± SD
Parameter	No Heparin (n = 9)	Prophylactic Heparin (n = 8)	Therapeutic Heparin (n = 6)	Overall (n = 23)
Time to major bleeding after transplant (days)	1.5 ± 1.2	2.7 ± 2.2	3.2 ± 1.5	2.3 ± 1.8
Hemoglobin (g/L)
Preoperative	129.4 ± 8.7	125.5 ± 11.2	120.5 ± 11.8	125.7 ± 10.6
Immediately after surgery	104.7 ± 12.9	108.6 ± 19.8	101.7 ± 8.6	105.3 ± 14.5
At time of bleeding event	77.2 ± 12.6	83.1 ± 16.9	74.3 ± 3.8	78.5 ± 12.8
Nadir after bleeding event	69.3 ± 11.3	72.1 ± 14.4	63.0 ± 4.4	68.7 ± 11.4
Decrease associated with bleeding	39.4 ± 8.7	41.8 ± 10.2	38.7 ± 6.3	40.0 ± 8.4
INR at time of event	1.4 ± 0.2	1.4 ± 0.4	1.2 ± 0.2	1.4 ± 0.3
PTT at time of event (s)	43.0 ± 23.7	38.0 ± 9.0	66.2 ± 41.4	47.3 ± 27.5
Platelet count at time of event (× 109/L)	95.0 ± 33.0	171.8 ± 84.9	133.5 ± 40.9	131.7 ± 64.8

INR = international normalized ratio, PTT = partial thromboplastin time, SD = standard deviation.