Fig. 6.

Sox9 conditional knock-out mice demonstrate reduced collagen at the lesion epicenter 14 weeks post-SCI. (A) Representative photomicrographs of Trichrome-stained spinal cord sections from the lesion epicenters of Sox9 conditional knock-out and control mice. (B) High power magnifications of boxed areas in A). (C) Quantification of area of collagen (blue) staining in Sox9 conditional knock-out and control sections. Areas of collagen staining were quantified as explained in legend to Figure 5. *Statistically significantly different from controls (P < 0.05, two-way ANOVA, Newman-Keuls post hoc test (P < 0.05); n = 9 Sox9 KO, n = 11 control). Bars = 100 μm.