Table 3.

Results of the multifactor dimension reduction analysis showing the best model of all possible 1- to 5-loci interactions and their outcome parameters

Model	Training accuracy*	Testing accuracy†	CVC‡	p value§
rs1800795	0.561	0.561	100/100	0.46
rs2272676–rs3027898	0.586	0.420	63/100	> 0.99
rs1800795–rs2272676–rs3027898	0.616	0.421	61/100	0.39
rs1800795–rs7744–rs2272676–rs3027898	0.661	0.406	44/100	0.99
rs1800795–rs7744–rs2272676–rs1143627–rs3027898¶	0.721	0.602	100/100	0.020

CVC = cross-validation consistency.

^*Accuracy in the 100-fold training data set.

^†Accuracy in the 100-fold testing data set.

^‡100-fold CVC.

^§p value of the best model corrected by 1000 permutations.

^¶Odds ratio 6.9 (95% confidence interval 4.4–10.6), p < 0.001, sensitivity 76.9%, specificity 67.3%, accuracy 72.1%, precision 69.9%.