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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Behav Brain Res. 2016 Mar 29;307:11–17. doi: 10.1016/j.bbr.2016.03.047

Figure 2.

Figure 2

Mice lacking FGF22 display normal anxiety-like behaviors. A. FGF22KO mice spend the same amount of time in closed and open parts of the elevated zero maze as WT littermates (two-way ANOVA, main effect of maze part, F1,96=107.9, p<0.0001; *** p<0.001, Tukey's HSD; main effect of genotype, F1,96=0, p>0.99; interaction effect, F1,96=0.55, p=0.46). B. FGF22KO and WT mice spend the same amount of time in the dark compartment of the light-dark box (two-way ANOVA, main effect of box part, F1,92=336.9, p<0.0001, *** p<0.001, Tukey's HSD; main effect of genotype, F1,92=0, p>0.99; interaction effect, F1,92=2.24, p=0.14). C. FGF22KO and WT mice spend the same amount of time in the periphery of the open field arena (two-way ANOVA, main effect of open field part, F1,26=842.9, p<0.0001, *** p<0.001, Tukey's HSD; main effect of genotype, F1,26=0, p>0.99; interaction effect, F1,26=0.64, p=0.43).