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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Antiviral Res. 2015 Jul 29;122:39–45. doi: 10.1016/j.antiviral.2015.07.008

Figure 4.

Figure 4

Co-treatment of SAHA with NITD008 improves outcome of lethal challenge with WNV: (A) SAHA was administered on days 3–6 or 5–9 after WNV inoculation, once per day and survival was monitored (B) Survival of mice treated with 100 mg/kg of SAHA or 10 mg/kg NITD008 alone was compared with mice treated with 100 mg/kg of SAHA and 10 mg/kg NITD008 on days 5–9 after inoculation (C) WNV titers in the brain at day 9 after infection from mice treated with SAHA (days 3–6 and 5–9) and SAHA plus NITD008 (days 5–9) using qRT-PCR. Error bars represent ± SEM from at least 4 mice/group.