Table 2.

Gene expression levels in brains of AA and normal mice

	Basal	Acute stress	Repeated stress
Hypothalamus
Crh	1.33	1.36	1.48
Avp	1.01	2.89	1.60
Esr1	−1.15	1.40	1.13
Esr2	−1.51	2.21	−1.06
Hippocampus
Esr1	−1.54	−1.16	1.00
Esr2	−1.47	−2.70	−1.27
Nr3c1	1.96	1.53	1.00
Nr3c2	−1.23	−1.60	−1.27
Pituitary
Pomc*	2.61	−1.01	2.76
Crhr1	1.15	1.46	1.30
Crhr2	−1.21	−1.17	1.42

AA, alopecia areata; Avp, arginine vasopressin; Crh, corticotropin-releasing hormone; Esr, estrogen receptor; Crhr, corticotropin-releasing hormone receptor; Nr3c, glucocorticoid receptor; Pomc, pro-opiomelanocortin.

Gene expression level of normal mice is set at ±1 fold. Significant differences are indicated in bold. All values are based on mean values from experiments conducted in triplicate for each mouse sample.

^*Pomc in the pituitary: acute stress<basal=chronic stress, P<0.05; AA: acute<chronic<basal, P<0.05.