Table 2. The diurnal variation of mean CT at five measure points during the two day measurements.

Time points	foveal CT		500 µm nasal		1500 µm nasal		500 µm temporal		1500µm temporal
	Median (IQR)a	P	Median (IQR)	P	Median (IQR)	P	Median (IQR)	P	Median (IQR)	P
The first daily measurement
8:00	243.5 (190.0,312.5)		241.0 (181.5,300.0)		196.0 (138.1,279.5)		262.8 (187.6,300.0)		243 (197.1,297.9)
11:00	244.0 (183.8,325.0)	0.01	246.5 (176.0,303.8)	0.009	200 (140.5, 275.0)	0.06	265.5 (187.6,300.0)	0.03	244 (196.1,286.6)	0.74
14:00	237.5 (194.0,323.8)	0.09	244.0 (176.5,294.0)	0.15	199.0 (134.0,274.8)	0.05	263.0 (188.4.,299.2)	0.1	240.0 (196.4,285.3)	0.13
17:00	231.5 (186.0,312.9)	0.99	237.2 (169.7, 287.9)	0.28	190.8 (132.5,247.8)	0.89	257.0 (186.0,297.8)	0.46	239.0 (199.2285.8)	0.29
20:00	228.5 (181.0,312.5)	0.03	235 (166.2,298.2)	0.16	195.0 (134.8,264.5)	0.56	251.5 (181.5,283.2)	0.55	237 (192.2,283.2)	0.17
Amplitude of CT	20.5 (13.0,31.0)		18.2 (10.3,28.5)		15.0 (9.5,21.0)		18.0 (10.2,28.0)		14.0 (7.5,26.2)
Pb	0.81	<0.001	0.80	<0.001	0.59	0.001	0.63	0.01	0.55	0.160
The second daily measurement
8:00	226 (188.8,285.8)	0.210	232.5 (185.8,275.2)	0.005	194 (139.2,231)	0.080	252.5 (214.2,284.8)	0.870	243 (212,278)	0.940
11:00	244 (197.8,291.8)	0.110	234.5 (192.2,294)	0.910	198.5 (144.2,241)	0.400	261.5 (223.5,288.2)	0.030	250.5 (218.5,280.2)	0.170
14:00	233.5 (197.8,284.5)	0.390	236.5 (179.8,289.8)	0.880	195 (143,245.5)	0.790	259.5 (210.5,284)	0.310	246.5 (215.8,276.8)	0.150
17:00	232 (191.2,289.2)	0.080	237 (179.8,284.5)	0.020	197.5 (141.2,237)	0.140	253 (213.5,286.8)	0.080	246.5 (211.2,274)	0.910
20:00	227 (189.2,290)	0.004	232 (183.5,286.5)	0.010	191 (141.5,240.5)	0.200	257 (211.8,288.2)	0.150	244.5 (212.2,274.5)	0.640
Amplitude of CT	20.0 (12.5,28.2)		20.0 (12.7,29.5)		14.0 (10.0,21.0)		20.5 (10.7,30.2)		20.5 (12.5,27.2)
Pb	0.72	<0.001	0.970	0.010	0.790	0.003	0.680	0.010	0.520	0.260

^aData are shown as median (IQR); ^bRepeated measurement ANOVA with Huynh-Feldt correction