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. 2016 Apr 28;7:11416. doi: 10.1038/ncomms11416

Figure 1. Schematic representation of the Virotrap strategy.

Figure 1

Expression of a GAG-bait fusion protein (1) results in submembrane multimerization (2) and subsequent budding of VLPs from cells (3). Interaction partners of the bait protein are also trapped within these VLPs and can be identified after purification by western blotting or MS analysis (4).