Table 7. Effectiveness of montelukast compared with placebo in the high ECP group (ECP ≥15 µg/L).
Changes after taking Montelukast (Mean±SD) |
Changes after taking Placebo drug (Mean±SD) |
P value | |
---|---|---|---|
SCORAD index | -2.2±10.5 | -7.8±11.2 | 0.21 |
Urine LTE4 (pg/mL) | -8.8± 557.9 | 146.8±487.0 | 0.44 |
Urine EDN (ng/mL) | -356.0±857.7 | -229.6±1,029.3 | 0.81 |
ECP, eosinophil cationic protein; SCORAD, SCORing Atopic Dermatitis; LTE4, leukotriene E4; EDN, eosinophil-derived neurotoxin.