Table 2. Correlation of local specific antibodies to D. farinae and inflammatory mediators with IL-33 and IL-25.
IL-33 | IL-25 | |||
---|---|---|---|---|
r | P value | r | P value | |
Total IgE* | -0.171 | 0.191 | 0.079 | 0.546 |
Specific IgE to D. farinae* | -0.162 | 0.216 | 0.218 | 0.095 |
Specific IgE to D. farinae† | -0.0186 | 0.164 | 0.141 | 0.283 |
Specific IgA to D. farinae† | -0.0186 | 0.156 | 0.086 | 0.516 |
Secretory IgA to D. farinae† | -0.199 | 0.127 | 0.072 | 0.583 |
ECP* | 0.017 | 0.900 | 0.025 | 0.850 |
Tryptase* | -0.173 | 0.187 | 0.021 | 0.873 |
IL-8† | -0.039 | 0.768 | 0.625 | <0.001 |
VEGF† | 0.025 | 0.851 | 0.084 | 0.523 |
IL-25† | -0.012 | 0.926 |
All values were adjusted by the protein ratio.
*Detected by using the ImmunoCAP method; †Measured by using ELISA; Pearson's rank correlation coefficients were applied to the test; All values were adjusted for the protein ratio.
D., Dermatophagoides; ECP, eosinophil cationic protein; IL, interleukin; VEGF, vascular endothelial growth factor.