| Geerts et al. (3) |
Single center prospective cohort, major trauma patients |
349 |
No |
58% (1% fatal PE) |
Age, blood transfusion, surgery, fracture of the femur or tibia, and spinal cord injury. |
| O'Malley et al. (6) |
Single center retrospective cohort, major trauma patients |
1,316 |
Yes |
2.3% (PE) |
Age > 55 years, multi-system injury, cannulation of central veins, and pelvic fractures (but not long-bone fractures) |
| Paffrath et al. (7) |
Multicenter retrospective cohort, major trauma patients |
7,937 |
Yes |
1.8% (PE) |
ISS score, Pelvic AIS score 2 or higher, # of operations, medical comorbidities (diabetes, renal failure, malignancy, coagulation disorders) |
| Tuttle-Newhall et al. (8) |
State-wide trauma registry, major trauma patients |
318,554 |
Yes |
0.3% (PE) |
Age > 55 years, increasing ISS and AIS (extremity, soft tissue, chest regions), |
| Godzik et al. (5) |
Retrospective Database Review, Ortho Trauma Patients |
199,952 |
Yes |
0.46% (PE) |
Multiple fractures, history of warfarin use, morbid obesity, ED disposition to ICU or OR |
| Fisher et al. (12) |
Prospective RCT (SCDs vs. None), Ortho Trauma Patients |
304 |
Yes/No |
11% vs. 4% |
11% incidence for control group, 4% incidence in experimental group |
| Stannard et al. (10) |
Prospective Cohort Study, Ortho Trauma Patients |
312 |
Yes |
11.5% |
11.5% incidence of VTE despite prophylaxis |
