Figure 1. Structure of nucleoside analogs.
The chemical structure (A), electrostatic potential map (B), and van der Waals volume (C) of deoxyuridine, thymidine, trifluridine (FTD), and bromodeoxyuridine (BrdU) are shown. Red circles in (A) are the C-5 positions of the pyrimidine rings in the analogs and molecular weights (MW) are shown. Red and blue regions in (B) indicate electron-rich and electron-poor regions, respectively. The C-5 positions of nucleosides in (B) are shown using arrows (FTD and BrdU) and arrowheads (thymidine). Green colors in FTD in (B) indicate fluorines.