Skip to main content
. 2016 May 3;6:25369. doi: 10.1038/srep25369

Table 2. Therapeutic efficacies stratified by RAM expression in IHCC.

  RAMhigh n = 18 RAMlow n = 62 p##
Objective response rate 22% (6–48) 24% (14–37) 1.000
Disease control rate# 39% (17–64) 53% (40–66) 0.423
Median PFS (months) 4.5 (1.8–8.5) 5.9 (4.2‒7.1) 0.533
Median OS (months) 5.7 (3.3–9.9) 11.7 (8.8–14.5) 0.021

RAM, ROS1/ALK/c-MET; IHCC, intrahepatic cholangiocarcinoma; PFS, progression - free survival; OS, overall survival.

#Disease control rate = complete response + partial response + stable disease >16 weeks.

##Objective response rates and disease control rates were compared using Fisher’s exact test, 2-tailed; PFS and OS were compared using log-rank tests.