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. 2016 May 3;6:25408. doi: 10.1038/srep25408

Table 3. Univariate and multivariate analyses of factors associated with PFS and OS1.

Parameters PFS
OS
Univariate2 Multivariate3
Univariate2 Multivariate3
P value Referent HR 95% CI P value P value Referent HR 95% CI P value
Age Continuous Variable 0.997 0.988 1.007 0.576 Continuous Variable 1.016 1.005 1.028 0.006
FIGO Stage <0.001 Advanced vs. Early 2.413 1.577 3.691 <0.001 <0.001 Advanced vs. Early 3.618 1.728 7.576 0.001
Residual Disease <0.001 RD vs. R0 1.633 1.324 2.015 <0.001 <0.001 RD vs. R0 1.958 1.457 2.631 <0.001
ER 0.036 Negative 1.302 1.077 1.573 0.006 0.150 Negative 1.288 1.014 1.636 0.038
PR 0.009 Negative 0.718 0.538 0.958 0.024 0.061 Negative 0.911 0.617 1.346 0.641
AR 0.368 Negative 0.982 0.813 1.185 0.847 0.023 Negative 0.744 0.578 0.959 0.022
FSHR 0.975 Negative 1.024 0.862 1.217 0.786 0.586 Negative 1.166 0.936 1.451 0.171
LHR 0.455 Negative 1.108 0.925 1.329 0.266 0.782 Negative 0.971 0.772 1.222 0.805
GnRHR 0.800 Negative 0.907 0.691 1.192 0.484 0.488 Negative 0.976 0.693 1.374 0.889
HER2 0.746 0 0.916 0.576 1.457 0.710 0.815 0 0.747 0.407 1.373 0.348
Ki67 0.021 Negative 0.835 0.683 1.021 0.079 0.003 Negative 0.688 0.520 0.910 0.009

1Numbers of patients (number of events/patients at risk): PFS (549/749), OS (345/875).

2Log-rank tests.

3Cox regression analysis expressed as hazard ratios.