Table 3.

Screening for CFRD

Patients	2002	2004	p Value
MWCFC total	1163	1316	–
Eligible for OGTT (no prior CFRD diagnosis)	1022	1092	–
Tested by OGTT	162	132	0.08*
Tested by FBG alone	109	149	0.12*
Screened at least once for CFRD by any method (% of total)	1054 (91)	982 (75)	<0.001*†
Confirmed with CFRD (% of total)	141 (12)	224 (17)	<0.001†

*Despite specific interventions to improve, screening procedures for CFRD failed to improve during the study. OGTT numbers and FBG measurements were unchanged while random blood glucose measurements were significantly reduced. Considering the more sensitive and specific combination of FBG alone or OGTT shows that 26.5% of all eligible patients in 2002 and 25.7% in 2005 were screened for CFRD in MWCFC study centers. The change in testing for this combination was not significantly improved. These observations cannot be explained by the increased numbers of patients included in the second chart review in the study.

†Although testing for CFRD decreased during the study, the number of patients with a diagnosis of CFRD significantly increased, a change not explained by the increase in overall population of patients with CF. Nationally, all CF centers had a decrease in screening using random blood glucose, FBG alone or OGTT from 80.5% in 2002 to 73.3% in 2004, a change that parallels the decrease in MWCFC centers.^{9 16}

CF, cystic fibrosis; CFRD, CF-related diabetes; FBG, fasting blood glucose; MWCFC, Mountain West CF Consortium; OGTT, oral glucose tolerance test.