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. Author manuscript; available in PMC: 2016 May 3.
Published in final edited form as: JAMA Ophthalmol. 2014 Mar;132(3):338–345. doi: 10.1001/jamaophthalmol.2013.5799

Figure 2. Micrograph and Autofluorescent Images.

Figure 2

There is variable loss of photoreceptor cells beyond the edge of geographic atrophy. Light micrographs and autofluorescent images of a 70-year-old male donor with bilateral geographic atrophy showing the edge of continuous retinal pigment epithelium (arrowhead) and a well-defined transition from geographic atrophy to retina with intact retinal pigment epithelium and rods and cones with outer segments (bracket; A and B). At another edge, the photoreceptor cells are restricted to a few cones with inner segments only (C and D). Over a distance of 1400 µm, only cones with few inner segments are seen (E and F). The Bruch membrane is irregularly thickened. The choriocapillaris is perfused throughout. Original magnification ×2500.