Table 2.
Summary of meta-regression of differences observed by each method
| Mean difference compared to cardiac MR |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Imaging modality | Year published | LVEDV (mL) (95% CI) | Overall p value | I2 p value |
LVESV (mL) (95% CI) | Overall p value | I2 p value |
LVEF (%) (95% CI) | Overall p value | I2 p value |
| 2D-echocardiography Volumes N=1579, LVEF N=1683 |
Overall | −33.26 (−43.42 to −20.65) | <0.0001 | 87% p<0.0001 | −16.20 (−21.36 to −11.04) | <0.0001 | 73% <0.0001 | −0.66 (−2.14 to 0.82) | 0.38 | 72% <0.0001 |
| <2005 | −23.23 (−43.86 to −2.59) | 0.03 | 77% p<0.0001 | −12.15 (−18.55 to --5.75) | 0.0002 | 0% 0.05 | −2.11 (−4.48 to 0.26) | 0.08 | 3% 0.40 | |
| 2005–2009 | −33.49 (−46.88 to −20.09) | <0.0001 | 90% p<0.0001 | −17.73 (−25.11 to −10.36) | <0.0001 | 81% <0.0001 | −0.26 (−2.32 to 1.81) | 0.81 | 81% <0.0001 | |
| >2009 | −46.46 (−72.27 to −20.65) | 0.0004 | 83% p<0.0001 | −18.73 (−29.46 to −8.01) | 0.0006 | 58% 0.05 | −1.14 (−3.03 to 0.21) | 0.09 | 0% 0.67 | |
| 2D-echocardiography with contrast Volumes and LVEF N=283 |
Overall* | −18.05 (−6.39 to −9.7) | <0.0001 | 0% p=0.45 | −7.84 (−14.46 to −1.22) | 0.02 | 0% p=0.99 | −1.03 (−3.38 to 1.35) | 0.39 | 0% p=0.61 |
| 3D-echocardiography Volumes N=1159, LVEF N=1104 |
Overall | −14.16 (−18.66 to −9.66) | <0.0001 | 23% p=0.12 | −6.49 (−9.91 to −3.07) | 0.0002 | 0% p=0.96 | 0.13 (−0.91 to 1.16) | 0.81 | 0% p=1.00 |
| <2005 | −15.14 (−25.17 to −5.12) | 0.003 | 0% p=0.49 | −6.38 (−13.36 to 0.60) | 0.07 | 0% p=0.91 | 0.25 (−2.09 to 2.59) | 0.83 | 0% p=1.00 | |
| 2005–2009 | −13.32 (−18.64 to −8.01) | <0.0001 | 43% p=0.01 | −6.27 (−10.41 to −2.13) | 0.003 | 0% p=0.72 | 0.02 (−1.20 to 1.23) | 0.98 | 0% p=0.99 | |
| >2009 | −18.95 (−34.54 to −3.36) | 0.02 | 0% p=0.86 | −8.77 (−21.00 to 3.47) | 0.16 | 0% p=0.84 | 0.89 (−2.93 to 4.70) | 0.65 | 9% p=0.33 | |
| Multidetector CT Volumes N=790, LVEF N=780 |
Overall | −1.16 (−4.14 to 1.83) | 0.45 | 0% p=0.90 | −0.11 (−2.40 to 2.18) | 0.93 | 0% p=0.96 | 0.86 (−0.21 to 1.94) | 0.12 | 0% p=0.55 |
| 2007–2009 | 5.21 (−2.13 to 12.54) | 0.16 | 0% p=0.74 | 2.59 (−1.19 to 6.36) | 0.18 | 0% p=0.93 | 0.45 (−1.27 to 2.17) | 0.51 | 0% p=0.94 | |
| >2009 | −2.41 (−5.68 to 0.85) | 0.15 | 0% p=0.99 | −1.68 (−4.56 to 1.21) | 0.25 | 0% p=0.97 | 1.13 (−0.25 to 2.50) | 0.11 | 4% p=0.40 | |
Values are mean (95% CI).
*Insufficient number of studies for subgroup analysis.
LVEDV, Left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume.