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. 2016 Mar 15;25(9):661–673. doi: 10.1089/scd.2015.0344

Table 2.

Distinct hBM Subpopulations Occupied Different Regions in CD18 Versus CD31 Plot

Population Lineage marker Region CD31 intensity CD18 intensity
Mesenchymal/erythroid CD105+ R1 Negative Negative
BM-MSCs MSCA-1+ R1 Negative Negative
Lymphoid CD3/CD20+ R2, R4, R5 Negative–dim–intermediate Dim–intermediate–bright
Myeloid CD66+ R3, R5 Intermediate Negative–bright
Monocytoid CD14+ R6 Bright Bright
Plasmacytoid CD138+ R7 Bright Negative
HSCs/EPCs CD34+ R3 Intermediate Negative
Pop#8 LinnegCD34negCD31+CD18+ R8 Bright– Dim–intermediate

Distribution of hBM subpopulations as defined by specific immunophenotypes resulted specific with the exception of lymphocytes that segregated into three different regions and myeloid cells that spread seamlessly from R3 to R5.

BM-MSCs, bone marrow–mesenchymal stromal cells; hBM, human bone marrow.