Table 1. Baseline characteristics of men with PCa in our cohort as well as histopathology results, by upgrade status.

	GS upgrade (n = 56 34%)	GS no-upgrade (n = 110 66%)	P-value
Mean age (SD)	67.1 (6.8)	64.9 (7.0)	0.06*
Mean PSA (SD)	8.85 (4.1)	7.7 (5.5)	0.21*
% of positive cores at initial biopsy (%)	15.1 (10.1)	14.3 (10.9)	0.64*
% of positive cores at confirmatory biopsy (%)	21.6 (15.6)	7.1 (9.4)	<0.01*
Ethnicity
White	38 (67.8%)	77 (70%)	0.37**
Black	10 (17.8%)	24 (21.8%)
Asian	2 (3.5%)	2 (1.81%)
Mixed	0	3 (2.71%)
Other/missing	5 (8.9%)	4 (3.63%)
Gleason score
3+3	0 (0%)	73 (66.3%)	<0.01**
3+4	42 (75.0%)	0 (0%)
4+3	11 (19.6%)	0 (0%)
4+5	3 (5.4%)	0 (0%)
2+3	0 (0%)	1 (0.9%)
Benign	0 (0%)	23 (20%)
HGPIN	0 (0%)	13 (11.8%)

^*T-test.

^**Chi-Square Test.