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. 2016 Apr 27;11:1717–1730. doi: 10.2147/IJN.S99890

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© 2016 Tong et al. This work is published and licensed by Dove Medical Press Limited

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Synthesis of linear-brush copolymer of PEG-b-(PELG-g-PLL).

Abbreviations: BLG, γ-benzyl l-glutamate; BTC, bis(trichloromethyl)carbonate; BLG-NCA, γ-benzyl l-glutamate-N-carboxyanhydride; PEG-NH₂: poly(ethylene glycol) amine; PEG-b-PBLG, poly(ethylene glycol)-b-poly(γ-benzyl l-glutamate); DMF, N, N-dimethylformamide; 2-HP, 2-hydroxypyridine; EA, ethylenediamine; PEG-b-PELG, poly(ethylene glycol)-b-poly(ethylenediamine l-glutamate); ZLL-NCA, ε-benzyoxycarbonyl-l-lysine-N-carboxyanhydride; PEG-b-(PELG-g-PZLL), poly(ethylene glycol)-b-(poly(ethylenediamine l-glutamate)-g-poly(ε-benzyoxycarbonyl-l-lysine)); PEG-b-(PELG-g-PLL), poly(ethylene glycol)-b-(poly(ethylenediamine l-glutamate)-g-poly(l-lysine)).