Table 1.
Patient demographics, clinical features, preceding events, and electrophysiological features in anti-GM2 antibody reactive and non-reactive dogs.
| Abs present n = 15 |
Abs absent n = 10 |
p | ||
|---|---|---|---|---|
| Patient demographics | Age (median) | 7.5 years | 9 years | 0.200* |
| Sex | 9m 6f | 7m 3f | 0.691† | |
| Sampling | Onset to serum acquisition | 10 days | 9.5 days | 0.504* |
| Clinical features | Ambulatory tetraparesis | 26.7% (n = 4) | 60.0% (n = 6) | 0.122† |
| Non-ambulatory paraparesis | 6.7% (n = 1) | 10.0% (n = 1) | 1.000† | |
| Non-ambulatory tetraparesis | 60.0% (n = 9) | 20.0% (n = 2) | 0.099† | |
| Tetraplegia | 6.7% (n = 1) | 10.0% (n = 1) | 1.000† | |
| Areflexia | 60.0% (n = 9) | 20.0% (n = 2) | 0.099† | |
| Hyperesthesia | 33.3% (n = 5) | 10.0% (n = 1) | 0.341† | |
| Involvement of CNs | 86.7% (n = 13) | 70.0% (n = 7) | 0.358† | |
| Respiratory compromise | 13.3% (n = 2) | 0.0% (n = 0) | 0.500† | |
| Pneumonia | 6.7% (n = 1) | 10.0% (n = 1) | 1.000† | |
| Death | 13.3% (n = 2) | 0.0% (n = 0) | 0.500† | |
| Preceding events | GIT infection | 13.3% (n = 2) | 20.0% (n = 2) | 1.000† |
| Respiratory infection | 6.7% (n = 1) | 0.0% (n = 0) | 1.000† | |
| Vaccination | 0.0% (n = 0) | 0.0% (n = 0) | − | |
| Electrophysiological features | Spontaneous activity in EMG | 100% (n = 15) | 90% (n = 9) | 0.400† |
| CMAP dispersion | 53.3% (n = 8) | 50.0% (n = 5) | 1.000† | |
| CMAP amplitude decreased | 93.3% (n = 14) | 70.0% (n = 7) | 0.267† | |
| F-waves normal | 0.0% (n = 0) | 20.0% (n = 2) | 0.150† | |
| F-waves prolonged latency | 80.0% (n = 12) | 80.0% (n = 8) | 1.000† | |
| F-waves not recordable | 20.0% (n = 3) | 0.0% (n = 0) | 0.250† |
Abs, antibodies; CMAP, compound muscle action potential; CNs, cranial nerves; EMG, electromyography; GIT, gastrointestinal.
Mann-Whitney U-test.
Fisherˊs exact test.