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. Author manuscript; available in PMC: 2016 May 3.
Published in final edited form as: J Neural Eng. 2016 Jan 29;13(2):026003. doi: 10.1088/1741-2560/13/2/026003

Figure 13.

Figure 13

LA-LPE3, 1051 days. (a) A typical electrode tip with thick encapsulation and minimal platinum tip degradation, scale 30 μm, 8 kV. (b) Top view of another electrode tip showing platinum erosion, silicon exposure, and tissue invasion, scale 1 μm, 5 kV. (c) Top view of parylene interface where delamination is difficult to assess because of thick fibrosis, scale 1 μm, 5 kV. (d) Top view of array showing abundant cellular material and thick fibrotic encapsulation, scale 200 μm, 5 kV. (e) Detail showing numerous cells at the base of an electrode with remnants of larger inter-electrode collagen fibers, scale 30 μm, 5 kV. (f) Close-up of fibroblasts on the base, scale 10 μm, 5 kV. (g) Detail showing individual collagen fibrils that compose encapsulation tissue, scale 2 μm, 5 kV. (h) Side view of an electrode shaft with thick fibrotic encapsulation tissue, scale 70 μm, 8 kV. (i) Side view of another electrode with fibroblasts actively depositing collagen, scale 100 μm, 8 kV.