Fig 4. Accumbal administration of NMU attenuates amphetamine-induced locomotor stimulation, but does not affect the expression of conditioned place preference in mice.
(A) Amphetamine-induced (2 mg/kg, ip) locomotor stimulation was attenuated by an accumbal injection of NMU (62.5 ng per side). Accumbal NMU administration had no effect per se on locomotor activity. (B) Accumbal NMU (62.5 ng per side, Amph-NMU) administration did not attenuate amphetamine-induced (2 mg/kg, ip, Amph-Veh) expression of CPP in mice. Data are presented as mean ± SEM (n.s. P>0.05, *P<0.05).