Table 3.
PedsQL median scores and adjusted linear or logistic regression results for associations of depression status with intelligence, achievement, and quality of life measures
| Outcome | Depressed (n=25) | Non-Depressed (n=319) | Effect estimate (95% CI) | |
|---|---|---|---|---|
| Unadjusted | Adjusted | |||
| Full Scale IQ | 88 [79, 97] | 99 [86, 109] | −11.00* (−17.57, −4.43) | −3.70 (−17.55, 10.16) |
| Achievement | 77.5 [72, 97] | 95 [83, 108] | −17.00* (−27.90, −6.10) | −11.24 (−22.50, 0.03) |
| Child Overall HRQoL | 57.5 [46, 72] | 78 [67, 86] | −20.00** (−31.07, −8.93) | −18.39** (−27.81, −8.96) |
| Child Physical HRQoL | 67.5 [48.5, 78] | 84 [72, 94] | −15.00** (−23.01, −6.99) | −15.46* (−25.13, −5.79) |
| Child Emotional HRQoL | 55 [40, 67.5] | 75 [60, 90] | −20.00*** (−27.86, −12.14) | −18.43*** (−27.31, −9.56) |
| Child Social HRQoL | 60 [37.5, 80] | 85 [70, 95] | −20.00 (−43.47, 3.47) | −14.23 (−32.53, 4.06) |
| Child School HRQoL | 50 [30, 60] | 65 [55, 75] | −15.00** (−23.17, −6.83) | −15.00* (−25.53, −4.47) |
| Parent Overall HRQoL | 54 [46, 72] | 76 [63, 87] | −22.00*** (−32.37, −11.63) | −15.48* (−28.71, −2.24) |
| Parent Physical HRQoL | 63 [47, 81] | 84 [66, 94] | −21.00* (−33.52, −8.48) | −16.97* (−30.94, −3.00) |
| Parent Emotional HRQoL | 55 [45, 75] | 75 [60, 90] | −20.00*** (−29.70, −10.30) | −17.76* (−31.77, −3.76) |
| Parent Social HRQoL | 55 [40, 80] | 80 [63, 95] | −25.00* (−42.45, −7.55) | −19.66 (−40.36, 1.03) |
| Parent School HRQoL | 40 [35, 55] | 65 [50, 80] | −25.00*** (−31.87, −18.13) | −21.35*** (−30.60, −12.11) |
| Odds ratio (95% CI) | ||||
| IEP/504 Plan Usage | 13 (52%) | 106 (33%) | 2.18 (0.96, 4.94) | 1.78 (0.74, 4.30) |
Median regression used for continuous variables, logistic used for IEP/504 Plan Usage. Adjusted Model controls for height z-score, maternal education, age, duration of CKD, and incontinence (defined as either day/night urine leakage or bedwetting after toilet training).
*
p<0.05;
**
p<0.001;
***
p<0.0001