Table 1.
Genes within the cAMP interactome that overlap with SNV mutations within human OS.
| cAMP int. | cAMP int. | cAMP int. | cAMP int. | Overlap(SNVs) |
|---|---|---|---|---|
| ABCC4 | CREB5 | MAP2K1 | ROCK1 | ADCY1 |
| ACOX1 | CREBBP | MAP2K2 | ROCK2 | ADRA1A |
| ACOX3 | DRD1 | MAPK1 | RRAS | ADRA2B |
| ADCY10 | DRD5 | MC2R | RRAS2 | AKAP1 |
| ADCY2 | EDNRA | MEK1 | SLC9A1 | AKAP3 |
| ADCY3 | EP300 | MEK2 | SOX9 | AKAP5 |
| ADCY4 | EPAC2 | MYL9 | SSTR1 | AKAP6 |
| ADCY5 | FFAR2 | NFAT2 | SSTR2 | ANXA1 |
| ADCY6 | FOS | NFATC | SUCNR1 | ATP1A1 |
| ADCY7 | FSH | NFATC1 | TIAM1 | ATP2B1 |
| ADCY8 | FSHR | NFKB1 | TNNI3 | CACNA1D |
| ADCY9 | FXYD1 | NFKBIA | TSHR | CACNA1F |
| ADCYAP1R1 | FXYD2 | NPY | VAV | CACNA1S |
| ADORA1 | GABBR | NPY1R | CFTR | |
| ADORA2A | GHRL | NR1C1 | DRD2 | |
| AF6 | GHSR | ORAI1 | F2R | |
| AKAP2 | GLI1 | OXTR | GIPR | |
| AKT | GLI3 | PACAPRI | GNAI3 | |
| AMH | GLP1R | PAK1 | GRIA2 | |
| ANPRA | GNAS | PKA | GRIN2A | |
| ARAP3 | GPR109 | PLCE | GRIN2B | |
| BAD | GPR119 | PLD1 | GRIN3A | |
| BDNF | GPR81 | PLN | HCN4 | |
| BRAF | GRIA1 | PPP1C | PDE10A | |
| CACNA1C | GRIA3 | PPP1R12A | PDE2A | |
| CALM | GRIA4 | PPP1R1B | PDE4B | |
| CAMK2 | GRIN1 | PTCH1 | PDE4D | |
| CAMK4 | GRIN2C | PTGER2 | PDE6B | |
| CHRM1 | GRIN2D | RAC1 | PIK3C2B | |
| CHRM2 | GRIN3B | RAC2 | PIK3CG | |
| c-Jun | HCN2 | RAC3 | PIK3R4 | |
| CNGA1 | HHIP | RAF1 | PIK3R6 | |
| CNGA2 | HTR1 | RAP1A | PPP2R2B | |
| CNGA3 | HTR4 | RAP1B | PPP2R3A | |
| CNGA4 | HTR6 | RAPGEF3 | PRKCA | |
| CNGB1 | JNK | RAPGEF4 | PRKCB | |
| CNGB3 | JUN | RELA | PTGER3 | |
| CREB1 | KAT3 | RHOA | RYR2 | |
| CREB3 | LIPE | VIPR2 | SSTR5 |