Table 1.
Distributions of demographics and lifestyle factors and glutathione-S-transferase (GST) genotypes of study subjects by the treatment sequence assignment The PEITC Intervention Study 2008–2013
| Characteristics at baselinea | Treatment sequence assignment
|
Total | ||
|---|---|---|---|---|
| PEITC-Placebo | Placebo-PEITC | Pb | ||
| Number of subjects | 41 | 41 | 82 | |
| Age (years), mean (SD) | 40.9 (10.6) | 41.1 (9.6) | 0.939 | 41.0 (10.1) |
| Body mass index (kg/m2), mean (SD) | 28.0 (4.8) | 28.0 (6.3) | 0.957 | 28.0 (5.6) |
| Gender, n (%) | 0.376 | |||
| Male | 24 (59) | 20 (49) | 44 (54) | |
| Female | 17 (41) | 21 (51) | 38 (46) | |
| Race, n (%) | 0.839 | |||
| Africa American | 8 (20) | 10 (24) | 18 (22) | |
| Caucasian American | 28 (68) | 27 (66) | 55 (67) | |
| Others | 5 (12) | 4 (10) | 9 (11) | |
| Level of education, n (%) | 0.179 | |||
| High school or lower | 14 (34) | 20 (49) | 34 (41) | |
| College or higher | 27 (66) | 21 (51) | 48 (59) | |
| Cigarette smoking, mean (SD) | ||||
| Cigarettes/day | 19.3 (6.6) | 19.0 (6.7) | 0.843 | 19.1 (6.6) |
| Years of smoking | 14.7 (10.3) | 17.9 (9.4) | 0.157 | 16.3 (9.8) |
| Age at starting smoking (year) | 15.2 (4.9) | 15.1 (4.6) | 0.963 | 15.1 (4.7) |
| Age became regular smokers (year) | 18.6 (7.1) | 17.7 (5.2) | 0.514 | 18.1 (6.2) |
| Alcohol drinking, n (%)† | 0.784 | |||
| Never | 14 (35) | 17 (42) | 31 (39) | |
| Monthly or less | 14 (35) | 12 (30) | 26 (32) | |
| Greater than monthly | 12 (30) | 11 (28) | 23 (29) | |
| GSTM1 & GSTT1 genotypes, n (%) | 0.585 | |||
| Both present | 20 (49) | 18 (44) | 38 (46) | |
| Present/null | 3 (7) | 4 (10) | 7 (9) | |
| Null/present | 14 (34) | 11 (27) | 25 (30) | |
| Both null | 4 (10) | 8 (19) | 12 (15) | |
a
Abbreviations: SD, standard deviation.
b
2-sided P for the difference between the two treatment assignment groups based on the two-group t-test (for continuous variables) or χ2 test (for nominal or categorical variables).
†
Two subjects were excluded from this analysis due to missing data.