FIG. 5.
Shape change was observed for platelets for several of the repeated shear stress and exposure time conditions. (A) Baseline platelets have a discoid shape, with little or no protrusions, which increase in length and number as the stress accumulation is increased. Conditions tested include (B) 228 dyne-s/cm2 (50 dyne/cm2 for 300 ms), (C) 1194 dyne-s/cm2 (250 dyne/cm2 for 60 ms), and (D) 2883 dyne-s/cm2 (500 dyne/cm2 for 63 ms). (E) A significant increase is noted only between the 711 dyne-s/cm2 (150 dyne/cm2 for 100 ms) condition and higher stress accumulations (p < 0.05).
