Fig. 6.

Bikaverin production by mutant Mut-4 in optimized medium open circle pH, filled circle DCW (g l⁻¹), filled square Glucose uptake rate (g l⁻¹ h⁻¹), filled triangle Bikaverin production rate (mg l⁻¹ h⁻¹). Fermentation was carried out in shake flasks, in triplicate, for 5 days at 28 °C, 200 rpm