Table 1.
Production of bikaverin by selected mutants of F. fujikuroi in 5 day shake flask experiments performed in triplicate
| Mutant | DCW g l−1 | Bikaverin mg l−1 | Bikaverin mg g−1 DCW | GA3 mg l−1 | GA3 mg g−1 DCW |
|---|---|---|---|---|---|
| NCIM 1019 | 11.8 ± 0.44 | 77 ± 3.78 | 6.52 | 16 ± .66 | 1.35 |
| Mut-1 | 6 ± 0.26 | 525 ± 2.0 | 87.5 | 107 ± 5.30 | 17.8 |
| Mut-2 | 5.5 ± 0.25 | 745 ± 4.73 | 135.0 | 103 ± 5.30 | 18.7 |
| Mut-3 | 6.1 ± 0.30 | 920 ± 7.93 | 150.0 | 55 ± .64 | 9.0 |
| Mut-4 | 5.4 ± 0.20 | 1715 ± 7.81 | 317.0 | 41 ± .65 | 7.6 |
| Mut-5 | 5.5 ± 0.25 | 263 ± 7.00 | 47.8 | 128 ± 6.03 | 23.2 |
| Mut-6 | 5.8 ± 0.30 | 475 ± 6.55 | 81.8 | 132 ± 6.56 | 22.7 |
| Mut-7 | 6.2 ± 0.10 | 912 ± 8.20 | 147.0 | 55 ± 2.09 | 8.8 |
| Mut-8 | 6 ± 0.26 | 426 ± 7.21 | 71.0 | 45 ± 2.08 | 7.5 |
| Mut-9 | 5.7 ± 0.20 | 520 ± 8.20 | 91.2 | 76 ± 3.60 | 13.3 |
| Mut-10 | 5.3 ± 0.26 | 484 ± 7.54 | 91.3 | 102 ± 4.16 | 19.2 |