Table 2.
The numbers of individual seizure types and percentage of seizure reduction.
| Seizure type | Active tDCS |
Sham tDCS |
p Value | ||||
|---|---|---|---|---|---|---|---|
| n | Mean (SD) | % Seizure reduction | n | Mean (SD) | % Seizure reduction | ||
| Tonic seizures | |||||||
| Baseline frequency | 9 | 21.27 (21.67) | 5 | 25.71 (22.63) | 0.663 | ||
| Day 1 | 8 | 9.40 (12.73) | 55.81 | 5 | 24.00 (23.61) | 6.65 | 0.071 |
| Day 2 | 7 | 5.00 (7.11) | 76.49 | 5 | 26.57 (22.98) | −3.35 | 0.003** |
| Day 3 | 2 | 0.47 (1.25) | 97.79 | 5 | 25.29 (21.08) | 1.63 | 0.000*** |
| Day 4 | 2 | 0.27 (0.80) | 98.73 | 5 | 28.57 (23.13) | −11.12 | 0.000*** |
| Day 5 | 1 | 0.20 (0.77) | 99.06 | 5 | 24.86 (21.48) | 3.31 | 0.000*** |
| Week 1 | 3 | 0.33 (0.72) | 98.45 | 5 | 29.57 (24.75) | −15.01 | 0.000*** |
| Week 2 | 7 | 2.00 (2.80) | 90.60 | 5 | 25.43 (22.52) | 1.09 | 0.001** |
| Week 3 | 7 | 5.07 (8.13) | 76.16 | 5 | 29.57 (24.75) | −15.01 | 0.001** |
| Week 4 | 8 | 9.33 (12.26) | 56.14 | 5 | 26.29 (22.88) | −2.26 | 0.033* |
| Atonic seizures | |||||||
| Baseline frequency | 7 | 19.20 (31.76) | 5 | 33.14 (36.32) | 0.370 | ||
| Day 1 | 6 | 8.00 (13.49) | 58.33 | 5 | 32.71 (33.79) | 1.30 | 0.022* |
| Day 2 | 6 | 3.80 (6.11) | 80.21 | 5 | 36.57 (38.32) | −10.35 | 0.003** |
| Day 3 | 5 | 2.67 (3.45) | 86.09 | 5 | 32.14 (33.18) | 3.02 | 0.002** |
| Day 4 | 1 | 0.27 (1.03) | 98.59 | 5 | 34.57 (33.07) | −4.32 | 0.001** |
| Day 5 | 0 | 0.00 (0.00) | 100.00 | 5 | 26.57 (24.24) | 19.82 | 0.000*** |
| Week 1 | 3 | 3.60 (12.08) | 81.25 | 5 | 37.29 (37.84) | −12.52 | 0.005** |
| Week 2 | 7 | 4.00 (7.60) | 79.17 | 5 | 32.14 (33.53) | 3.02 | 0.005** |
| Week 3 | 7 | 4.80 (8.25) | 75.00 | 5 | 38.00 (41.03) | −14.67 | 0.006** |
| Week 4 | 7 | 7.40 (9.55) | 61.46 | 5 | 33.86 (38.50) | −2.17 | 0.019* |
| Absence seizures | |||||||
| Baseline frequency | 9 | 20.47 (22.97) | 4 | 23.14 (26.56) | 0.811 | ||
| Day 1 | 9 | 9.60 (12.02) | 53.10 | 4 | 25.57 (28.73) | −10.50 | 0.076 |
| Day 2 | 9 | 5.80 (6.55) | 71.67 | 4 | 25.71 (29.09) | −11.11 | 0.018* |
| Day 3 | 4 | 1.33 (2.50) | 93.50 | 4 | 23.00 (26.43) | 0.61 | 0.004** |
| Day 4 | 4 | 0.80 (1.52) | 96.09 | 4 | 23.57 (26.16) | −1.86 | 0.002** |
| Day 5 | 2 | 0.53 (1.60) | 97.41 | 4 | 23.86 (26.22) | −3.11 | 0.002** |
| Week 1 | 2 | 1.80 (5.95) | 91.21 | 4 | 21.86 (25.78) | 5.53 | 0.008** |
| Week 2 | 7 | 4.27 (6.26) | 79.14 | 4 | 23.86 (27.82) | −3.11 | 0.015* |
| Week 3 | 8 | 5.53 (7.24) | 72.98 | 4 | 23.14 (27.12) | 0.00 | 0.026* |
| Week 4 | 8 | 8.60 (10.52) | 57.99 | 4 | 21.00 (24.61) | 9.25 | 0.108 |
| Myoclonic seizures | |||||||
| Baseline frequency | 7 | 15.93 (21.31) | 1 | 7.86 (20.79) | 0.414 | ||
| Day 1 | 7 | 8.67 (12.97) | 45.57 | 1 | 8.57 (22.68) | −9.03 | 0.990 |
| Day 2 | 7 | 5.67 (7.84) | 64.41 | 1 | 7.14 (18.90) | 9.16 | 0.795 |
| Day 3 | 5 | 2.13 (3.74) | 86.63 | 1 | 8.00 (21.17) | −1.78 | 0.299 |
| Day 4 | 2 | 0.80 (2.24) | 94.98 | 1 | 9.00 (23.81) | −14.50 | 0.189 |
| Day 5 | 0 | 0.00 (0.00) | 100.00 | 1 | 7.71 (20.41) | 1.91 | 0.147 |
| Week 1 | 3 | 2.53 (6.94) | 84.12 | 1 | 8.86 (23.43) | −12.72 | 0.338 |
| Week 2 | 6 | 4.20 (6.66) | 73.63 | 1 | 7.86 (20.79) | 0.00 | 0.536 |
| Week 3 | 6 | 5.93 (8.71) | 62.77 | 1 | 7.00 (18.52) | 10.94 | 0.854 |
| Week 4 | 6 | 8.20 (12.07) | 48.52 | 1 | 8.00 (21.17) | −1.78 | 0.978 |
| Partial seizures | |||||||
| Baseline frequency | 4 | 3.13 (6.80) | 1 | 3.57 (9.45) | 0.902 | ||
| Day 1 | 4 | 1.93 (4.38) | 38.34 | 1 | 4.57 (12.09) | −28.01 | 0.455 |
| Day 2 | 4 | 1.00 (1.89) | 68.05 | 1 | 3.86 (10.21) | −8.12 | 0.295 |
| Day 3 | 2 | 0.27 (0.70) | 91.37 | 1 | 4.00 (10.58) | −12.04 | 0.177 |
| Day 4 | 0 | 0.00 (0.00) | 100.00 | 1 | 3.86 (10.21) | −8.12 | 0.147 |
| Day 5 | 0 | 0.00 (0.00) | 100.00 | 1 | 3.43 (9.07) | 3.92 | 0.147 |
| Week 1 | 0 | 0.00 (0.00) | 100.00 | 1 | 4.00 (10.58) | −12.04 | 0.147 |
| Week 2 | 4 | 0.73 (1.49) | 76.68 | 1 | 3.14 (8.32) | 12.04 | 0.278 |
| Week 3 | 4 | 0.93 (1.83) | 70.29 | 1 | 3.00 (7.94) | 15.97 | 0.339 |
| Week 4 | 4 | 2.00 (3.55) | 36.10 | 1 | 4.00 (10.58) | −12.04 | 0.510 |
*p < 0.05, **p < 0.01, ***p < 0.001.