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SIRT1 expression and activity. (A) SIRT1 expression in aorta of young and old control (YC and OC) and young and old NMN‐supplemented (YNMN and ONMN) mice (n = 5–7 per group). (B) Ratio of acetylated to total NFκB in aorta (n = 5–11 per group). Data are expressed relative to α‐smooth muscle actin and normalized to YC mean value. Representative Western blot images below. Values are mean ± SEM. #P < 0.05 vs. YC; †P < 0.05 vs. OC.
