Table 1.
Parameters | Predominantly classic | Minimally classic | Occult with no classic |
---|---|---|---|
Cumulative probability of change in vision | |||
Usual care at 1 year | |||
Gain of >3 lines | 2.41% | 1.92% | 2.17% |
Loss of 3–6 lines | 23.10% | 28.85% | 22.83% |
Loss of >6 lines | 29.14% | 16.35% | 32.61% |
Usual care at 2 years | |||
Gain of >3 lines | 1.48% | 2.89% | 1.71% |
Loss of 3–6 lines | 6.33% | 6.33% | 6.33% |
Loss of >6 lines | 4.21% | 10.57% | 14.13% |
PDT at 1 year | |||
Gain of >3 lines | 5.66% | 6.44% | 3.01% |
Loss of 3–6 lines | 26.51% | 27.23% | 28.92% |
Loss of >6 lines | 13.46% | 16.83% | 22.29% |
PDT at 2 years | |||
Gain of >3 lines | 1.75% | 1.98% | 1.81% |
Loss of 3–6 lines | 6.35% | 5.44% | 8.16% |
Loss of >6 lines | 3.00% | 2.97% | 6.63% |
RR of ranibizumab versus PDT | |||
at 1 year | |||
Gain of >3 lines | 7.2 | N/A | N/A |
Loss of 3–6 lines | 0.1 | N/A | N/A |
Loss of >6 lines | 0 | N/A | N/A |
at 2 years | |||
Gain of >3 lines | 0.49 | N/A | N/A |
Loss of 3–6 lines | 4.35 | N/A | N/A |
Loss of >6 lines | 0.06 | N/A | N/A |
RR of ranibizumab versus usual care | |||
at 1 year | |||
Gain of >3 lines | N/A | 6.69 | 6.69 |
Loss of 3–6 lines | N/A | 0.17 | 0.17 |
Loss of >6 lines | N/A | 0.09 | 0.09 |
at 2 years | |||
Gain of >3 lines | N/A | 0.42 | 0.42 |
Loss of 3–6 lines | N/A | 3.78 | 3.78 |
Loss of >6 lines | N/A | 0.14 | 0.14 |
RR of bevacizumab versus ranibizumab | |||
at 1 and 2 years | |||
Gain of >3 lines | 0.92 | 0.92 | 0.92 |
Loss of 3–6 lines | 1.07 | 1.07 | 1.07 |
Loss of >6 lines | 1.07 | 1.07 | 1.07 |
RR: risk ratio.
N/A: not applicable.