Table 2. Effect of treatments on Bifidobacterium and Lactobacillus populations of the fecal microbiota of the volunteers (median (IQR)).
| Bacterial concentrations (log 16S rRNA gene copies/g) |
Control (n=10) |
Orlistat (n=10) |
Orlistat–Prebiotic (n=10) |
Prebiotic (n=11) |
P (KW) |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| T0 | T1 | T0 | T1 | T0 | T1 | T0 | T1 | T0 | T1 | |
| Lactobacillus spp. | 6.18 (5.96–7.34) | 6.01 (5.83–6.20) | 6.47 (6.01–6.84) | 6.00 (5.76–6.55) | 6.23 (6.06–6.68) | 6.03 (5.87–6.30) | 6.33 (6.08–6.86) | 6.08 (5.71–6.64) | 0.90 | 0.65 |
| Bifidobacterium spp. | 8.39 (8.08–8.88) | 7.97 (7.44–9.02) | 8.00 (7.61–8.30) | 8.02 (6.81–8.52) | 7.87 (7.38–8.31) | 8.35a (7.76–8.92) | 8.07 (7.47–8.25) | 8.61 (7.88–9.01) | 0.12 | 0.54 |
IQR, interquartile range; KW, Kruskal–Wallis. The last column (P) shows the level of significance for the comparisons of the four groups by Kruskal–Wallis analysis of variance at T0 and T1 for both parameters. No differences were observed between groups at T0 and T1.
a
A significant increase of Bifidobacterium spp. was observed at T1 in the OP group (P=0.028). A similar tendency was observed for the P group (P=0.07).