Fig. 2.

DA^Tph2−/− rats had reduced growth and increased mortality. A: DA^Tph2−/− rats were smaller beginning at P7 and remained smaller thereafter up to 60 days of age (P < 0.001, two-way ANOVA). B: weights of DA^Tph2−/− rats (green) ware expressed as a percentage of the WT weight at each age and plotted across age (days). C: survival (%pups born for each genotype) at each postnatal (P) age showed that after an initial high rate of mortality in DA^Tph2−/− pups there was additional mortality on or after P10 that was rare in control [WT and heterozygous (Het)] pups.