Table 1.
Forebrain levels of monoamines in two mutant lines of adult male control and DATph2−/− rats
| Mutation/Genotype | 5-HT | Norepinephrine | Dopamine |
|---|---|---|---|
| M2 | |||
| WT (n = 3) | 495.5 ± 24.1 | 382.2 ± 6.2 | 2424.7 ± 57.0 |
| Het (n = 3) | 401.9 ± 43.0 | 403.6 ± 28.9 | 2,047.9 ± 125.5 |
| DATph2−/− (n = 3) | Not detectable | 358.7 ± 22.1 | 1918.4 ± 51.5 |
| M3 | |||
| WT (n = 2) | 439.1 ± 4.9 | 368.6 ± 15.7 | 2,098.3 ± 63.0 |
| Het (n = 4) | 442.5 ± 20.7 | 411.3 ± 24.9 | 2,414.5 ± 168.7 |
| DATph2−/− (n = 4) | Not detectable | 362.7 ± 20.0 | 2,142.9 ± 60.7 |
Values are means ± SE in ng/g. 5-HT, serotonin; WT, wild-type; Het, heterozygous; DATph2−/−, homozygous mutant.