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. 2016 Apr 25;6(4):e206. doi: 10.1038/nutd.2016.12

Figure 1.

Figure 1

Improved glucose tolerance in mice with adenovirus-mediated overexpression of LPCAT3. C57BL/6 mice were injected with adenovirus encoding either human LPCAT3 (filled bars and symbols) or LacZ (open bars and symbols). (a) Western blot analysis of LPCAT3 protein levels 2 days after adenovirus injection. The inset shows representative western blot images of LPCAT3 levels relative to tubulin levels in the respective livers. The data represent mean±s.d. from three separate experiments (total N=6). (b) Glucose tolerance was performed 2 days after injection. Mice were fasted overnight and blood glucose levels were measured before and after feeding a bolus lipid-glucose mixed meal. (c) Area under the curve analysis of data from the glucose tolerance tests. The glucose tolerance data represent mean±s.d. from two separate experiments each performed with three mice in each group (total N=6). The data were analyzed by t-test (a, c) or ANOVA (b) with * denotes differences from the LacZ group at P<0.05.