Table 2. Thigh composition variables by group and time point.

Thigh composition variable	Group	BL			5 months				23 months
		Mean	s.d.	Between-group P-value	Mean	s.d.	Δ from BL P-value	Between-group P-value	Mean	s.d.	Δ from BL P-value	Δ from 5 months P-value	Between-group P-value
Total thigh volume (cm3)	RT	1549	144	0.01	1557	133	0.77	<0.01	1494	136	0.08	0.02	0.2
	RT+CR	1377	122		1289	88.6	<0.01		1330	120	0.16	0.19
Thigh muscle volume (cm3)	RT	664.4	140	0.85	695.8	166	0.01	0.01	671.1	154	0.61	0.04	0.11
	RT+CR	653.4	140		652.7	142	0.9		636.7	129	0.03	0.01
Thigh fat volume (cm3)	RT	763.2	208	0.13	763.2	240	0.99	<0.01	751.4	209	0.57	0.62	0.59
	RT+CR	634.2	197		534	152	<0.01		617.5	180	0.48	<0.01
Thigh subcutaneous fat volume (cm3)	RT	732.5	209	0.16	733.7	241	0.9	<0.01	720.1	213	0.53	0.56	0.65
	RT+CR	609.6	199		514.9	153	<0.01		593	183	0.48	<0.01
Thigh Intermuscular Fat Volume (cm3)	RT	30.7	19.7	0.32	29.5	16.2	0.37	0.01	31.3	22.7	0.82	0.47	0.53
	RT+CR	24.6	8		19.1	6.9	<0.01		24.5	9.6	0.95	<0.01

Sample sizes per group: RT=11, RT+CR=13. Within-group comparisons are estimated from mixed linear models adjusting for baseline mean values of the change variable from 0 to 5 and 5 to 23 months. Between-group comparisons estimated from mixed linear models adjusted for baseline mean values using contrasts for 5- and 23-month group means.

Abbreviations: BL, baseline; CR, caloric restriction; RT, resistance training.