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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Lancet. 2010 Jul 31;376(9738):367–387. doi: 10.1016/S0140-6736(10)60829-X

Figure. Emerging medical comorbidity and mortality in HIV-infected drug users.

Figure

This graph depicts the relative proportion of comorbidities over time if antiretroviral therapy (ART) is widely accessed. ART results in marked reductions in AIDS-related opportunistic infections and malignant diseases. Although ART also decreases several non-AIDS-related morbidities through a reduction in cytokine production and inflammatory responses, over time these comorbidities will increasingly contribute to mortality, but not as profoundly as mortality before availability of ART.