Fig. 1.
Freezing in HDID-1, HDID-2, and HS mice in Experiment 1 (5-day protocol) before stimulus presentations (Pre), during Tone (with or without shock), and during intertrial intervals (ITI). For conditioning and testing parameters, temporal data binning strategy, and statistical outcomes, see the text. Percent time spent freezing ± SE is shown. Panel A. Acquisition (Day 1). Shock group data are shown in filled bars, and No Shock group data in open bars. Periods of tone CS presentation culminated with 2-s shocks on this day for the Shock groups. Panel B. Context testing (Day 2). No tones or shocks were presented during this test period. Panel C. Cued testing in the novel context (Day 3). Two, 180-s tone CS periods occurred, with no shocks presented.
